A Rare Kind of Lymphoma in a Patient on Treatment With Two Different Biological Agents

Inesa ARSTIKYTE1,2, Irena BUTRIMIENE1,2, Agne PETRULIONIENE1, Algirdas VENALIS1,2

1Vilnius University, Centre of Rheumatology, 2State Research Institute, Centre for Innovative Medicine, Research, Vilnius, Lithuania

Keywords: Cutaneous pseudo lymphoma, drug induced pseudo lymphoma, infliximab, rituximab, treatment of pseudolymphoma

Abstract

In this article, we present a rare case of cutaneous pseudolymphoma which developed after treatment with two biologics: infliximab and rituximab. Cutaneous pseudolymphoma should be considered in the differential diagnosis of B- or T-cell lymphoma, which may present not only with local lesions, but also systemic features like fever, weight loss, night sweating, fatigue, and tiredness. In our case, skin biopsy with immunohistochemistry confirmed diagnosis of cutaneous pseudolymphoma. Treatment with systemic corticosteroids was effective.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.