Tofacitinib Induced Psoriasiform Lesion in a Patient With Rheumatoid Arthritis
Kemal Erol1, Ragıp Ertaş2
1Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Kayseri City Hospital, Kayseri, Turkey
2Department of Dermatology, Kayseri City Hospital, Kayseri, Turkey
Keywords: Paradoxical, psoriasis, rheumatoid arthritis, tofacitinib
Paradoxical psoriasis or psoriasiform lesion is an adverse effect, represented by the occurrence of a psoriasiform lesion or exacerbation of psoriasis caused by the drugs normally used for the management of psoriasis. In this article, we present the first case of a 45-year-old male patient with rheumatoid arthritis who developed psoriasiform lesions following treatment with tofacitinib, and highlight the possible pathogenetic mechanisms involved in such an occurrence.