Jia WANG, Xi XIE, Fen LI, Jinwei CHEN

Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China

Keywords: Multiple myeloma; Sjögren's syndrome; systemic lupus erythematosus


Patients with rheumatic diseases are at an increased risk for malignant lymphoproliferative disease, but the coexistence of rheumatic diseases and multiple myeloma is uncommon. Herein, we report a rare case of systemic lupus erythematosus and Sjögren's syndrome, which preceded the development of multiple myeloma after three years. We also summarize the clinical features of this case and discuss the possible pathogenetic mechanisms that underlie this unusual association.