Sui RUBO, 1 Lei ZHANG2

1Department of Neurology, First Affiliated Hospital of Liaoning Medical College, China
2Department of Nursing, School of Nursing of Liaoning Medical College, China

Keywords: Central pontine myelinolysis, hypokalemia; primary Sjogren's syndrome; quadriplegia; renal tubular acidosis


In this case report, we present a-75-year-old female case of primary Sjogren's syndrome (pSS) with distal renal tubular acidosis (RTA) as revealed by severe hypokalemia along with normal anion gap metabolic acidosis and abnormally acidified urine. The patient had a brain stem lesion as confirmed by quadriplegia, hypersomnia, and dysphagia. Laboratory tests revealed that the anti-Ro/SSA and anti-La/SSB antibodies were positive. Magnetic resonance imaging of the brain showed a hyperintense signal at T1 and T2 in the mid-pons, a typical characteristic of central pontine myelinolysis.