Gözde ZEYBEK1, Sevinç KALIN2, Burcu KARAKAYALI1, Ebru ZEMHERİ3, Sait NADERİ4, Betül SÖZERİ5

1Department of Pediatrics, Ümraniye Training and Research Hospital, Istanbul, Turkey
2Department of Pediatric Radiology, Ümraniye Training and Research Hospital, Istanbul, Turkey
3Department of Pathology, Ümraniye Training and Research Hospital, Istanbul, Turkey
4Department of Neurosurgery, Ümraniye Training and Research Hospital, Istanbul, Turkey
5Department of Pediatric Rheumatology, Ümraniye Training and Research Hospital, Istanbul, Turkey

Keywords: Fibrosis, immunoglobulin G4-related disease, lumbar vertebral involvement.

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory disease characterized by a tumor-like infiltration of IgG4 positive plasma cells and fibrosis in various organs. The exact pathogenesis remains unknown. In this article, we discuss the diagnostic management of IgG4-RD with reference to clinical, serologic, pathological and radiological data on a 17-year-old male patient with lumbar vertebral involvement.

Citation: Zeybek G, Kalın S, Karakayalı B, Zemheri E, Naderi S, Sözeri B. Unusual Presentation of Immunoglobulin G4-Related Disease: A Case Report. Arch Rheumatol 2021;36(x):i-vi.