Published In
Archives of Rheumatology
Volume 38 · Issue 4
Pages: 542-548
History
Published Online: December 31, 2023
This work is licensed under a Creative Commons Attribution 4.0 International License.
Matheus Costa
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Igor Jorge
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Patricia Martin
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Renato Nisihara
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Thelma Skare
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Matheus Costa, Igor Jorge, Patricia Martin, Renato Nisihara, & Thelma Skare. (2023). Males and females with scleroderma: A comparative study in a Brazilian sample. Archives of Rheumatology, 38(4), 542–548. https://doi.org/10.46497/ArchRheumatol.2023.10011
Abstract
Objectives: This study aimed to evaluate the clinical and serological profile in systemic sclerosis (SSc) by comparing females and males.
Patients and methods: This retrospective study was conducted with 215 SSc patients (193 females, 22 males; mean age: 50.1±14.5 years; range, 16 to 88 years) between September 2005 and September 2020. Disease severity was calculated by the Medsger severity score. Males and females were compared for clinical and serological markers.
Results: Females more frequently had esophageal involvement (p=0.003), telangiectasias (p=0.03), and antinuclear antibodies (p=0.04). Males more frequently had fingertip scars (p=0.03), digital ulcers (p=0.006), and a worse median Medsger severity score (6 in males vs. 4 in females, p=0.05).
Conclusion: In the studied sample, males had more severe disease than females with greater repercussions in periferic circulatory system.
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Article Info
Published In
Journal
Archives of Rheumatology
Volume / Issue
Volume 38 · Issue 4
Pages
542-548
History
Published Online
December 31, 2023
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Affiliations
Matheus Costa
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Igor Jorge
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Patricia Martin
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Renato Nisihara
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Thelma Skare
Department of Medicine, Mackenzie Evangelical School of Medicine, Curitiba, Brazil
Cite this Article
Matheus Costa, Igor Jorge, Patricia Martin, Renato Nisihara, & Thelma Skare. (2023). Males and females with scleroderma: A comparative study in a Brazilian sample. Archives of Rheumatology, 38(4), 542–548. https://doi.org/10.46497/ArchRheumatol.2023.10011
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