Case Report

Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review

Volume 34 · Issue 3 · September 2019 Publish Date: September 30, 2019
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DOI
Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China image/svg+xml
Shu LI, Cong DENG, Jinwei CHEN, & Fen LI. (2019). Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review. Archives of Rheumatology, 34(3), 343–347. https://doi.org/10.5606/ArchRheumatol.2019.7070
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Abstract

Mikulicz’s disease (MD), an immunoglobulin G4 (IgG4)-related disease, is a fibrosis-associated inflammatory disease characterized by painless bilat- eral swelling of lacrimal and salivary glands. Although thrombocytopenia is associated with many rheumatologic disorders, it is rare in IgG4-related MD. This novel study aims to report a rare case of IgG4-related MD complicated with severe autoimmune thrombocytopenia without any hemato- logical malignancies and review all cases of IgG4-related disease associated with thrombocytopenia in the literature.

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Published In
Journal Archives of Rheumatology
Volume / Issue Volume 34 · Issue 3 · September 2019
Pages 343-347
History
Published Online September 30, 2019
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1
Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
2
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
3
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
4
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Cite this Article
Shu LI, Cong DENG, Jinwei CHEN, & Fen LI. (2019). Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review. Archives of Rheumatology, 34(3), 343–347. https://doi.org/10.5606/ArchRheumatol.2019.7070
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