Amra Adrovic1, Mehmet Yıldız2, Fatih Haşlak2, Sezgin Şahin2, Oya Köker3, Aybüke Günalp2, Kenan Barut2, Özgür Kasapçopur2

1Pediatric Rheumatology, Koç University Hospital, Istanbul, Türkiye
2Pediatric Rheumatology, Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Istanbul, Türkiye
3Pediatric Rheumatology, Marmara University Faculty of Medicine, Istanbul, Türkiye

Keywords: Coronavirus disease 2019, interstitial lung disease, juvenile systemic sclerosis, SARS-CoV-2, tocilizumab.


Objectives: This study aimed to explore the influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic among patients with juvenile systemic sclerosis (JSS).

Patients and methods: Twenty-seven patients (22 females, 5 males; mean age: 20 years; range, 17 to 22 years) diagnosed with JSS and followed up at the department of pediatric rheumatology were included in the cross-sectional study. A web-based survey was performed by focusing on patients’ complaints, accessibility to health care, and compliance with routine treatment from January 1, 2021, to January 10, 2021.

Results: Five (18.5%) patients had deterioration of the disease, while six (22.2%) patients reported irregular usage of their routine scleroderma treatment during the last six months. Nine (33.3%) patients had missed their routine clinic control since the proclamation of the SARS-CoV-2 pandemic. Seven (25.9%) patients had household contact with coronavirus disease 2019 (COVID-19). Four (14.8%) patients were diagnosed with COVID-19, and only one (3.7%) was hospitalized. Nine patients were under biological treatment (tocilizumab); however, only one of them was diagnosed with COVID-19.

Conclusion: The COVID-19 pandemic has not significantly disrupted the medical care of JSS patients. Telemedicine could be an acceptable option for JSS patients disenabled to come to the hospital.

Citation: Adrovic A, Yıldız M, Haşlak F, Şahin S, Köker O, Günalp A, et al. The impact of COVID-19 on clinical course and treatment among patients with juvenile systemic sclerosis. Arch Rheumatol 2023;38(x):i-vii.